Back Cover

Cover of Linfield’s sesquicentennial boo

Spatially Varying X-ray Synchrotron Emission in SN 1006

A growing number of both galactic and extragalactic supernova remnants show non-thermal (non-plerionic) emission in the X-ray band. New synchrotron models, realized as SRESC and SRCUT in XSPEC 11, which use the radio spectral index and flux as inputs and include the full single-particle emissivity, have demonstrated that synchrotron emission is capable of producing the spectra of dominantly non-thermal supernova remnants with interesting consequences for residual thermal abundances and acceleration of particles. In addition, these models deliver a much better-constrained separation between the thermal and non-thermal components, whereas combining an unconstrained powerlaw with modern thermal models can produce a range of acceptable fits. While synchrotron emission can be approximated by a powerlaw over small ranges of energy, the synchrotron spectrum is in fact steepening over the X-ray band. Having demonstrated that the integrated spectrum of SN 1006, a remnant dominated by non-thermal emission, is well described by synchrotron models I now turn to spatially resolved observations of this well studied remnant. The synchrotron models make both spectral and spatial predictions, describing how the non-thermal emission varies across the remnant. Armed with spatially resolved non-thermal models and new thermal models such as VPSHOCK we can now dissect the inner workings of SN 1006.Comment: 4 pages, 4 figures. To appear in "Young Supernova Remnants" the 11th Annual October Maryland Astrophysics Conference AIP eds. Steve Holt and Una Hwan

Senior secondary school students' risk of disengagement from further education, employment or training

In Western Australia, the school leaving age was mandated to rise from 15 Years to 16 Years in 2007. This policy has resulted in a large number of students remaining at school and entering the senior years of schooling. Of interest in this study were the students who would not normally have remained at school, particularly those who may have disengaged from schooling. Data were obtained from school and education district office student services staff on 23 attributes of 5313 Year Ten students identified at risk of not completing schooling, future training or entering employment. The data were dichotomous and the multi-variate nature of these data rendered it unsuitable for Rasch Model analysis but amenable to interpretation using Binomial Logistic Regression. Two models were tested with each containing a different dependent variable and common independent variables. The dependent variables for the respective models were: Model 1 - Student Risk of Disengagement; and Model 2 - Student Severe Risk of Disengagement. The study identified particular student attributes perceived by school and district office student services staff that statistically predicted two levels of disengagement with schooling, future training or future employment

Understanding what principals value about leadership, teaching and learning: A philosophical approach

Contemporary views of educational leadership are increasingly focussed on two aspects of the role of school principals - the affective qualities of school leaders and the attention given to pedagogy within the school. Moral and ethical values are seen as important considerations in the leadership role and in the training of school leaders. Understanding the nature of principal value systems including the processes by which particular values develop is an important area of leadership theorising and empirical research. One way forward in this field is to apply a philosophical approach in which value systems are considered as a manifestation of educational philosophy. With regard to leading pedagogy, effective leadership of teacher instruction and student learning is also contingent on the philosophical orientation of the principal. That is, the influence of the principal on the school's pedagogy is dependent on how strongly the principal values this dimension of the leadership role. The authors contend there is a need to investigate exercise of pedagogic leadership within schools from the perspective of philosophic inquiry - to ask questions about the ontology, epistemology and methodology applied by principals as leaders of teaching and learning in the school

The tempo of cultural change in the Kostenki Upper Paleolithic : further insights

open access via Cambridge University Press agreement This work was funded by the Leverhulme Trust (AHOB3 and RPG-2012-800). We thank the staff of the ORAU past and present for their careful laboratory work. We also thank the reviewers and Editor-in-Chief for their comments. AB and AS acknowledge Russian Science Foundation grant numbers 20-78-10151 and 18-78-00136, and Russian Foundation of Basic Research grant numbers 18-39-20009, 18-00-00837 and 20-09-00233. We also acknowledge the participation of IHMC RAS (state assignment 0184-2019-0001) and ZIN RAS (state assignment АААА-А19-119032590102-7). We thank the UK Natural Environment Research Council (NERC) for supporting the Oxford node of the National Environmental Isotope Facility (NEIF).Peer reviewedPublisher PD

Comparative analysis of 37 Acinetobacter bacteriophages

© 2017 by the authors. Licensee MDPI, Basel, Switzerland. Members of the genus Acinetobacter are ubiquitous in the environment and the multipledrug resistant species A. baumannii is of significant clinical concern. This clinical relevance is currently driving research on bacterial viruses infecting A. baumannii, in an effort to implement phage therapy and phage-derived antimicrobials. Initially, a total of 42 Acinetobacter phage genome sequences were available in the international nucleotide sequence databases, corresponding to a total of 2.87 Mbp of sequence information and representing all three families of the order Caudovirales and a single member of the Leviviridae. A comparative bioinformatics analysis of 37 Acinetobacter phages revealed that they form six discrete clusters and two singletons based on genomic organisation and nucleotide sequence identity. The assignment of these phages to clusters was further supported by proteomic relationships established using OrthoMCL. The 4067 proteins encoded by the 37 phage genomes formed 737 groups and 974 orphans. Notably, over half of the proteins encoded by the Acinetobacter phages are of unknown function. The comparative analysis and clustering presented enables an updated taxonomic framing of these clades

Expanding the Operational Use of Total Lightning Ahead of GOES-R

NASA's Shortterm Prediction Research and Transition Center (SPoRT) has been transitioning realtime total lightning observations from groundbased lightning mapping arrays since 2003. This initial effort was with the local Weather Forecast Offices (WFO) that could use the North Alabama Lightning Mapping Array (NALMA). These early collaborations established a strong interest in the use of total lightning for WFO operations. In particular the focus started with warning decision support, but has since expanded to include impactbased decision support and lightning safety. SPoRT has used its experience to establish connections with new lightning mapping arrays as they become available. The GOESR / JPSS Visiting Scientist Program has enabled SPoRT to conduct visits to new partners and expand the number of operational users with access to total lightning observations. In early 2014, SPoRT conducted the most recent visiting scientist trips to meet with forecast offices that will used the Colorado, Houston, and Langmuir Lab (New Mexico) lightning mapping arrays. In addition, SPoRT met with the corresponding Center Weather Service Units (CWSUs) to expand collaborations with the aviation community. These visits were an opportunity to learn about the forecast needs of each office visited as well as to provide onsite training for the use of total lightning, setting the stage for a realtime assessment during MayJuly 2014. With five lightning mapping arrays covering multiple geographic locations, the 2014 assessment has demonstrated numerous uses of total lightning in varying situations. Several highlights include a much broader use of total lightning for impactbased decision support ranging from airport weather warnings, supporting fire crews, and protecting large outdoor events. The inclusion of the CWSUs has broadened the operational scope of total lightning, demonstrating how these data can support air traffic management, particularly in the Terminal Radar Approach Control Facilities (TRACON) region around an airport. These collaborations continue to demonstrate, from the operational perspective, the utility of total lightning and the importance of continued training and preparation in advance of the Geostationary Lightning Mapper

Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial.

$\textbf{BACKGROUND}$: Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65-70% of patients. We aimed to assess the medium-term effects and costs of psychological therapies on maintenance of reduced depression symptoms 12 months after treatment. $\textbf{METHODS}$: We did this multicentre, pragmatic, observer-blind, randomised controlled superiority trial (IMPACT) at 15 National Health Service child and adolescent mental health service (CAMHS) clinics in three regions in England. Adolescent patients (aged 11-17 years) with a diagnosis of DSM IV major depressive disorder were randomly assigned (1:1:1), via a web-based randomisation service, to receive cognitive behavioural therapy (CBT) or short-term psychoanalytical therapy versus a reference brief psychological intervention. Randomisation was stochastically minimised by age, sex, self-reported depression sum score, and region. Patients and clinicians were aware of group allocation, but allocation was concealed from outcome assessors. Patients were followed up and reassessed at weeks 6, 12, 36, 52, and 86 post-randomisation. The primary outcome was self-reported depression symptoms at weeks 36, 52, and 86, as measured with the self-reported Mood and Feelings Questionnaire (MFQ). Because our aim was to compare the two psychological therapies with the brief psychosocial intervention, we first established whether CBT was inferior to short-term psychoanalytical psychotherapy for the same outcome. Primary analysis was by intention to treat. This trial is registered with Current Controlled Trials, number ISRCTN83033550. $\textbf{FINDINGS}$: Between June 29, 2010, and Jan 17, 2013, we randomly assigned 470 patients to receive the brief psychosocial intervention (n=158), CBT (n=155), or short-term psychoanalytical therapy (n=157); 465 patients comprised the intention-to-treat population. 392 (84%) patients had available data for primary analysis by the end of follow-up. Treatment fidelity and differentiation were established between the three interventions. The median number of treatment sessions differed significantly between patients in the brief psychosocial intervention group (n=6 [IQR 4-11]), CBT group (n=9 [5-14]), and short-term psychoanalytical therapy group (n=11 [5-23]; p<0·0001), but there was no difference between groups in the average duration of treatment (27·5 [SD 21·5], 24·9 [17·7], 27·9 [16·8] weeks, respectively; Kruskal-Wallis p=0·238). Self-reported depression symptoms did not differ significantly between patients given CBT and those given short-term psychoanalytical therapy at weeks 36 (treatment effect 0·179, 95% CI -3·731 to 4·088; p=0·929), 52 (0·307, -3·161 to 3·774; p=0·862), or 86 (0·578, -2·948 to 4·104; p=0·748). These two psychological treatments had no superiority effect compared with brief psychosocial intervention at weeks 36 (treatment effect -3·234, 95% CI -6·611 to 0·143; p=0·061), 52 (-2·806, -5·790 to 0·177; p=0·065), or 86 (-1·898, -4·922 to 1·126; p=0·219). Physical adverse events (self-reported breathing problems, sleep disturbances, drowsiness or tiredness, nausea, sweating, and being restless or overactive) did not differ between the groups. Total costs of the trial interventions did not differ significantly between treatment groups. $\textbf{INTERPRETATION}$: We found no evidence for the superiority of CBT or short-term psychoanalytical therapy compared with a brief psychosocial intervention in maintenance of reduced depression symptoms 12 months after treatment. Short-term psychoanalytical therapy was as effective as CBT and, together with brief psychosocial intervention, offers additional patient choice for psychological therapy, alongside CBT, for adolescents with moderate to severe depression who are attending routine specialist CAMHS clinics.National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme, and the Department of Health

Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial.

BACKGROUND: Psychological treatments for adolescents with unipolar major depressive disorder are associated with diagnostic remission within 28 weeks in 65-70% of patients. We aimed to assess the medium-term effects and costs of psychological therapies on maintenance of reduced depression symptoms 12 months after treatment. METHODS: We did this multicentre, pragmatic, observer-blind, randomised controlled superiority trial (IMPACT) at 15 National Health Service child and adolescent mental health service (CAMHS) clinics in three regions in England. Adolescent patients (aged 11-17 years) with a diagnosis of DSM IV major depressive disorder were randomly assigned (1:1:1), via a web-based randomisation service, to receive cognitive behavioural therapy (CBT) or short-term psychoanalytical therapy versus a reference brief psychological intervention. Randomisation was stochastically minimised by age, sex, self-reported depression sum score, and region. Patients and clinicians were aware of group allocation, but allocation was concealed from outcome assessors. Patients were followed up and reassessed at weeks 6, 12, 36, 52, and 86 post-randomisation. The primary outcome was self-reported depression symptoms at weeks 36, 52, and 86, as measured with the self-reported Mood and Feelings Questionnaire (MFQ). Because our aim was to compare the two psychological therapies with the brief psychosocial intervention, we first established whether CBT was inferior to short-term psychoanalytical psychotherapy for the same outcome. Primary analysis was by intention to treat. This trial is registered with Current Controlled Trials, number ISRCTN83033550. FINDINGS: Between June 29, 2010, and Jan 17, 2013, we randomly assigned 470 patients to receive the brief psychosocial intervention (n=158), CBT (n=155), or short-term psychoanalytical therapy (n=157); 465 patients comprised the intention-to-treat population. 392 (84%) patients had available data for primary analysis by the end of follow-up. Treatment fidelity and differentiation were established between the three interventions. The median number of treatment sessions differed significantly between patients in the brief psychosocial intervention group (n=6 [IQR 4-11]), CBT group (n=9 [5-14]), and short-term psychoanalytical therapy group (n=11 [5-23]; p<0·0001), but there was no difference between groups in the average duration of treatment (27·5 [SD 21·5], 24·9 [17·7], 27·9 [16·8] weeks, respectively; Kruskal-Wallis p=0·238). Self-reported depression symptoms did not differ significantly between patients given CBT and those given short-term psychoanalytical therapy at weeks 36 (treatment effect 0·179, 95% CI -3·731 to 4·088; p=0·929), 52 (0·307, -3·161 to 3·774; p=0·862), or 86 (0·578, -2·948 to 4·104; p=0·748). These two psychological treatments had no superiority effect compared with brief psychosocial intervention at weeks 36 (treatment effect -3·234, 95% CI -6·611 to 0·143; p=0·061), 52 (-2·806, -5·790 to 0·177; p=0·065), or 86 (-1·898, -4·922 to 1·126; p=0·219). Physical adverse events (self-reported breathing problems, sleep disturbances, drowsiness or tiredness, nausea, sweating, and being restless or overactive) did not differ between the groups. Total costs of the trial interventions did not differ significantly between treatment groups. INTERPRETATION: We found no evidence for the superiority of CBT or short-term psychoanalytical therapy compared with a brief psychosocial intervention in maintenance of reduced depression symptoms 12 months after treatment. Short-term psychoanalytical therapy was as effective as CBT and, together with brief psychosocial intervention, offers additional patient choice for psychological therapy, alongside CBT, for adolescents with moderate to severe depression who are attending routine specialist CAMHS clinics. FUNDING: National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme, and the Department of Health.National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme, and the Department of Health